Humboldt's Mathematics and Natural sciences Campus made the move to Adlershof between 1998 and 2003. It includes the Institutes of Chemistry, Geography, Computer science, Mathematics, Physics and Psychology with around 7,000 students and 1,000 staff members.

Library, computer and multimedia services are located in the Erwin Schrödinger Center. A wide range of services, job and internship opportunities are available at the online portal for students.

11 institutes with a staff of 1,600 – many of which with roots in the former East German Academy of Science – are working in the fields of light, materials and models: BAM (analytical chemistry, reference materials) // BTU (air chemistry) // DLR (planetary research, transportation systems) // FBH (high frequency technology) // Fraunhofer FIRST (computer architecture, software engineering) // HZB (materials, energy) // IKZ (crystal growth) // ISAS (analytical sciences) // MBI (nonlinear optics, short pulse spectroscopy) // PTB (photon radiometry)

The institutes' umbrella organization is the "Joint Initiative of Non-University Research Institutions in Adlershof" IGAFA.

3D-television, super-effective solar cells, traffic free highways, ultra-clear Mars cameras, the brightest light for mega-microscopes, energy saving light from light diodes, pure silicon counted to the last atom, thought powered machines... that’s what we research here in Adlershof.

• Optical Technology and photonics: opto-electronics and nano-optics // uv- and x-ray technology // laser research and techniques // OT in traffic and space research
  
• Information Technology: software technology simulation // signal processing // virtual realities
• Sustainable ressources: environmental research // energy technologies // photovoltaics
  
• Material research and microsystem technology: new materials // new processes // catalysis research // nanotechnolgies