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26. February 2018

Best of two worlds: combining optical tweezers with time-resolved confocal microscopy

PicoQuant and Ionovation now offer an integrated platform that combines microscopy and force spectroscopy

PicoTweezer. Bild: PicoQuant
Bild: PicoQuant

As a joint development, PicoQuant and Ionovation combined time-resolved microscopy and optical tweezers in a single system. Both instruments retain their individual functionalities but can also be used together, thus enabling customers to carry out time-resolved fluorescence microscopy (e.g. fluorescence lifetime imaging) on trapped objects such as cells.

PicoQuant‘s MicroTime 200 platform is the most flexible and extensible high-end research tool for time-resolved fluorescence microscopy requiring single molecule sensitivity. The system is an excellent choice for many methods, including Pulsed Interleaved Excitation (PIE), Förster Resonance Transfer (FRET), Stimulated Emission Depletion (STED) super-resolution microscopy, Fluorescence (Lifetime) Correlation Spectroscopy (F(L)CS), and anisotropy measurements.

Ionovation’s PicoTweezers system is a compact, robust trapping and force measurement device based on the “optical tweezers” concept which is equipped with real-time video detection. In contrast to common optical tweezers systems, PicoTweezers has no spatial restrictions and is compatible to all sample carriers. The system is well suited for molecular interaction studies, force spectroscopy, cell trapping, rheology and many other applications.

 

About PicoQuant

PicoQuant is a leading research and development company specializing in optoelectronics, which was founded in 1996. The company, based in the science and technology park of Berlin-Adlershof, Germany, is a worldwide leader in the field of single photon counting applications. The product portfolio encompasses picosecond pulsed diode lasers and LEDs, photon counting instrumentation, fluorescence lifetime spectrometers, FLIM and FCS upgrade kits for laser scanning microscopes as well as time-resolved confocal and super-resolution microscopes. Since April 2008 Sales and Support in North America is handled by PicoQuant Photonics North America Inc. The PicoQuant group employs currently around 80 people.

Contact

Marta Kolonko
Marketing
Tel.: +49 30 1208820-0
mkt(at)picoquant.com
www.picoquant.com

 

About Ionovation

Founded in 2004, Ionovation represents a wealth of experience in the development, integration and automation of complementary technical and scientific systems in the fields of life-sciences. Ionovation's unique combination of modern analytical methods with a broad range of microscopy techniques translates into a product line ranging from automated lipid bilayer (BLM) workstations to robust and easy to use optical tweezers for unprecedented force spectroscopy applications as well as industry compliant 3D-cell culture and Organ-on-Chip supply systems.

Contact

Dr. Karsten Gall
Ionovation GmbH
Gewerbepark 9-11, 49143 Bissendorf, Germany
Tel.: +49 5402 968979-30
contact(at)ionovation.com
www.ionovation.com

Analytics Photonics / Optics

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New microscope installed at the University of Leeds

PicoQuant teamed up with JPK Instruments to provide a highly sensitive tool for a wide range of life science applications, from molecules to cells
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The development of the Science and Technology Park Berlin Adlershof was and is co-financed by the European Union namely by EFRE. This concerns infrastructure development like construction of technology centres. Furthermore EFRE is used for international projects.

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